Seleco 100mg Tablet 10 'S

Seleco 100mg Tablet 10 'S belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAID) which are used for moderate to severe pain relief alone or in combination. It also helps in combating signs of inflammation including swelling, stiffness, tenderness, and pain in conditions such as osteoarthritis, rheumatoid arthritis, dysmenorrhea, juvenile rheumatoid arthritis, and muscle pain.  

Seleco 100mg Tablet 10 'S is chemically composed of Celecoxib, which particularly inhibits COX-2, unlike other NSAIDs that are non-specific inhibitors of COX 1 and 2. These work by blocking inflammatory mediators and reducing pain and swelling. NSAIDs carry an increased risk of side effects on gastrointestinal including ulceration, bleeding, etc. Seleco 100mg Tablet 10 'S must not be prescribed to people with long-standing heart disease due to the potential risk of myocardial infarction.

How Does Seleco 100mg Tablet 10 'S Work

Seleco 100mg Tablet 10 'S contains celecoxib as an active ingredient. It is by therapeutic classification, a COX-2 inhibitor that works by blocking the production of prostaglandins, a major group of chemicals involved in the inflammatory response. Prostaglandins are naturally occurring substances in the body that stimulate the inflammatory pathways when the immune system gets triggered. This way, celecoxib reduces the inflammation, swelling, and pain experienced by the patient.

Seleco 100mg Tablet 10 'S is prescribed to adults above 18 years of age to treat pain and swelling due to: 

• Rheumatoid arthritis
• Acute pain
• Juvenile rheumatoid arthritis
• Osteoarthritis 
• Ankylosing spondylitis 
• Dysmenorrhea 

Dosage

It is advised to start the treatment with a minimally effective dose which can be increased up to 400 mg if needed (do not take more than 400 mg).

Adult Dosage

Rheumatoid arthritis: 100 mg to 200 mg, twice daily.

Osteoarthritis: 100 mg twice a day, or 200 mg once a day.

Ankylosing spondylitis: 100 mg twice a day, or 200 mg once a day.

Dysmenorrhea: 400mg on day 1, then reduce the dose to 200 mg if needed. The maintenance dose is 200 mg twice a day.

Acute Pain: 400 mg once as starting dose, lower the dose to 200 mg twice a day.

Pediatric Dose

Seleco 100mg Tablet 10 'S is not prescribed to children and adolescents under 18 years of age

Elderly Dose

Seleco 100mg Tablet 10 'S is processed majorly by the liver, therefore while administering the drug to elderly patients careful consideration must be given to liver and renal function while deciding upon the dose, especially if the elderly are underweight (less than 50 kgs). 

Pregnancy Use And Lactation

Seleco 100mg Tablet 10 'S is classified as a pregnancy category C (up to 3rd trimester)) and D (towards the end of the 3rd trimester) drug, meaning there is an increased risk of harmful effects to the fetus, it is known to cause heart defects in babies. If you are pregnant, think you may be pregnant, or are planning to conceive a baby, please do not use it before consulting your doctor before using Seleco 100mg Tablet 10 'S. If it is accessary to take Seleco 100mg Tablet 10 'S, your doctor may advise you to start contraception. 

Seleco 100mg Tablet 10 'S is also secreted in human milk in minute quantity, if you are breastfeeding, please consult your doctor before taking Seleco 100mg Tablet 10 'S. 

How To Use Seleco 100mg Tablet 10 'S

Seleco 100mg Tablet 10 'S is available in form of capsules to be taken orally by swallowing, once or twice daily, or as directed by the doctor. It is advised to have Seleco 100mg Tablet 10 'S with food if it causes an upset stomach. Avoid consumption along with antacids.

• Stomach upset (nausea, vomiting, diarrhea)
• Flatulence 
• Dizziness 
• Heartburn
• Fatigue  

These effects tend to get mild and resolve in a few days of taking Seleco 100mg Tablet 10 'S.

Precautions

Please tell your doctor about any of the following conditions before using Seleco 100mg Tablet 10 'S

• Asthmatic patients should avoid taking Seleco 100mg Tablet 10 'S without medical supervision.
• Mild to moderate heart conditions may aggravate without any forewarning signs, make sure to consult a doctor first before taking Seleco 100mg Tablet 10 'S
• NSAIDs are likely to elevate blood pressure, so it is advised to monitor your B.P when taking Seleco 100mg Tablet 10 'S
• If you have a history of ulcers or bleeding ulcers, inform your doctor first before using the drug
• If you are taking blood thinners like warfarin, monitor your PT, carefully it may increase your chance to bleed
• Use of other regular NSAIDs like ibuprofen, and naproxen should be avoided concurrently with Seleco 100mg Tablet 10 'S
• Please be careful if you have diabetes, hypercholesterolemia or you are a heavy smoker
• Alcohol consumption must be avoided with Seleco 100mg Tablet 10 'S
• When treating elderly patients with Seleco 100mg Tablet 10 'S, the dosage is set carefully to avoid side effects
• In case of a pregnancy, or if you are planning to conceive a baby/ breastfeeding before starting Seleco 100mg Tablet 10 'S always ask your doctor first

Contraindications

Please tell your doctor if you have a history of any of the following before using Seleco 100mg Tablet 10 'S:

• Allergy to Seleco 100mg Tablet 10 'S or similar drugs or sulfonamide antibiotics 
• Asthmatics (aspirin-associated asthma)
• Gastrointestinal bleeding/perforation
• Gastric ulceration 
• Inflammatory diseases of the gut like colitis, Crohn's disease
• Severe kidney impairment/ failure
• Severe liver impairment/ failure
• Chronic heart disease 
• History of or a scheduled Coronary Artery Bypass Graft surgery
• Pregnancy 

Few medicines can interact with Seleco 100mg Tablet 10 'S some of which are enlisted below. Please tell your doctor about the use of the following before using Seleco 100mg Tablet 10 'S:

• Anticoagulants like warfarin, apixaban 
• Methotrexate
• ACE Inhibitors like enalapril
• Sulphonamides
• Diuretics
• Lithium
• Cyclosporin
• SSRIs
• Other NSAIDs
• Neuroleptics
• Carbamazepine
• Barbiturates 
• Dextromethorphan 
• Fluconazole 
• Rifampicin 
• Digoxin

#1. Is it safe to have antacids for indigestion along with Seleco 100mg Tablet 10 'S?

Yes, antacids are safe to be ingested by the patient while undergoing treatment with Seleco 100mg Tablet 10 'S. But take your antacid drug 2 hours before or after the dose as it may affect the absorption of the drug.

#2. Is it safe to have Seleco 100mg Tablet 10 'S along with other painkillers?

Over-the-counter analgesics like paracetamol are safely taken with Seleco 100mg Tablet 10 'S. However, do not take aspirin, ibuprofen, naproxen, or diclofenac-based analgesics as these might increase the risk of GI bleeding. 

#3. Can I drive after taking this medication?

This medication, in general, is not known to make you dizzy but, if that happens kindly avoid driving or operating any heavy or sharp machinery.

#4. How to store Seleco 100mg Tablet 10 'S?

Seleco 100mg Tablet 10 'S is to be kept away from the reach of children, in a cool dry place away from direct sunlight and humidity as that tends to ruin certain drugs.

#5. Will Seleco 100mg Tablet 10 'S affect my fertility?

Seleco 100mg Tablet 10 'S may disturb your fertility making it difficult to get pregnant, if this happens consult your doctor right away

#6. Will Seleco 100mg Tablet 10 'S cause me to gain weight?

As a part of its side effects Seleco 100mg Tablet 10 'S may cause you to gain weight or cause edema and water retention in your body. You should immediately consult a doctor if this happens