Lefora 20mg Tablet 10 'S

Lefora 20mg Tablet 10 'S is used to treat symptoms like stiff, swollen, and painful joints that are commonly seen in patients diagnosed with rheumatoid arthritis, osteoarthritis, and similar illnesses. Lefora 20mg Tablet 10 'S belongs to a group of drugs known as DMARDs (Disease-modifying antirheumatic drugs) and mainly work by blocking the natural chemical pathways of the immune system, that cause inflammation in the human body.

How Does Lefora 20mg Tablet 10 'S Work

Lefora 20mg Tablet 10 'S works by preventing the immune system from carrying out its functions thereby decreasing the inflammation happening at the joints. It acts as an immune modulator and produces its effects by the inhibition of pyrimidine synthesis.

Lefora 20mg Tablet 10 'S can be used to treat:

• Active rheumatoid arthritis
• Active psoriatic arthritis 

Dosage

Adult Dosage

Patients are commonly been prescribed a high dosage (loading dose) e.g 100 mg for one to three days after which 10 or 20 mg of the maintenance dose is prescribed.

Child Dosage

There isn't sufficient evidence to suggest that Lefora 20mg Tablet 10 'S is safe for patients under the age of 18 years 

Pregnancy Use And Lactation

This drug is not to be taken or prescribed to expecting and lactating mothers as it may have fatal consequences for the unborn child, especially if taken in the third trimester of pregnancy. If you are taking the drug and become pregnant, inform your doctor immediately, the doctor will ask you to stop using Lefora 20mg Tablet 10 'S and is likely to replace it with a different pregnancy-safe drug. Small amounts of this drug can be transferred to the child through breast milk and therefore cause adverse effects in the child thus Lefora 20mg Tablet 10 'S isn't recommended to lactating mothers. If you are planning to conceive and are taking Lefora 20mg Tablet 10 'S as treatment, then refer to the doctor. The physician is likely to change your medicine and dosage.

How To Use Lefora 20mg Tablet 10 'S

Lefora 20mg Tablet 10 'S is prescribed to be taken once daily,; orally (by mouth) either with or without food. The patient is advised to maintain hydration by the intake of a sufficient amount of fluids unless limited by the prescriber.

Like most medicines,Lefora 20mg Tablet 10 'S has certain side effects which include:

• Weakness
• Lightheadedness
• Dizziness
• Mouth ulcers
• Flu-like symptoms 
• Stomach problems (such as diarrhea, nausea, vomiting)
• Headaches 
• Abdominal cramps

These effects tend to be mild and resolve in a few days of taking Lefora 20mg Tablet 10 'S.

Precautions

Please tell your doctor about any of the following conditions before using Lefora 20mg Tablet 10 'S:

• Mild to moderate liver impairment
• Mild to moderate kidney impairment

Contraindications

Please tell your doctor if you have a history of any of the following before using Lefora 20mg Tablet 10 'S:

• Allergy to Lefora 20mg Tablet 10 'S or any other medicine or food substance 
• Moderate to severe liver impairment/disease
• Moderate to severe kidney impairment/disease
• Hypoproteinemia 
• AIDs
• Autoimmune disorders
• Pregnant women
• Breastfeeding women
• Low red blood cell count 
• Low white blood cell count 
• Low platelet count 
• Suffering from any active infection

Please tell your doctor about the use of the following before using Lefora 20mg Tablet 10 'S:

• Other DMARDs
• Alcohol
• Hepatotoxic (liver-damaging) drugs 
• Haemotoxic (poisonous to blood) drugs
• Methotrexate
• Drugs metabolized by CYP2C9 (not NSAIDs)
• Live vaccines
• Cholestyramine
• Activated charcoal.

#1. Why is cholestyramine prescribed after treatment with Lefora 20mg Tablet 10 'S?

The contents of Lefora 20mg Tablet 10 'S can stay in the human body for up to two years after when the treatment ends. Therefore, to remove it immediately and effectively from the body, patients are prescribed cholestyramine.

#2. How to store Lefora 20mg Tablet 10 'S?

Lefora 20mg Tablet 10 'S is to be kept away from the reach of children, in a cool dry place away from direct sunlight and humidity as that tends to ruin certain drugs.

#3. What if I take too much of Lefora 20mg Tablet 10 'S?

 An extra dose or two of Lefora 20mg Tablet 10 'S is not known to cause any harm but excess ingestion of Lefora 20mg Tablet 10 'S is a cause for concern and should be avoided and immediately reported to the doctor as it may lead to serious side effects such as fainting, breathlessness, and irregular heartbeats.

#4. What if I miss a dose of Lefora 20mg Tablet 10 'S?

If you miss a dose of the medication, make sure you take it as soon as possible on that same day. If you don’t remember you missed the dose until the next dosage time or the next day, do not double the dose and take your medication as per schedule.

#5. Will Lefora 20mg Tablet 10 'S affect my sexual activity?

No, there isn't sufficient evidence to suggest that patients experience a decrease in libido.

#6. Can I take Lefora 20mg Tablet 10 'S during my pregnancy?

No,Lefora 20mg Tablet 10 'S is deemed unsafe to be ingested during pregnancy.

#7. What lab tests will be prescribed while treatment with Lefora 20mg Tablet 10 'S and how often?

Kidney and liver function tests along with blood tests to keep a check on serum potassium levels are advised to be done periodically. It is also advised that patients learn to monitor their own blood pressure levels daily from the comfort of their homes and inform their doctor of any changes seen.

#8. Is it safe to have Lefora 20mg Tablet 10 'S along with oral contraceptives?

Yes. There is no evidence to suggest that Lefora 20mg Tablet 10 'S interacts with oral contraceptives.

#9. Can Lefora 20mg Tablet 10 'S cause dizziness? If so, how should I manage it?

Yes. It can cause dizziness as one of the most common side effects. If this happens, you should sit or lie down until the symptoms pass. However, please note this is temporary and usually goes away as the treatment continues. It is also advised to avoid the consumption of alcohol during the course of your treatment, as it may worsen the dizziness.

#10. Does Lefora 20mg Tablet 10 'S cause addiction?

No. This drug has shown no evidence to prove addiction of any kind in any patient.

#11. How long will I have to continue taking the medication?

It is a long-term treatment and you might have to continue taking the medication even for the rest of your life.

#12. Can I consume alcohol with Lefora 20mg Tablet 10 'S?

Alcohol is also known to lower your blood pressure which if taken with the medication may lead to extreme dizziness. It is best to avoid the intake of alcohol during the course of your treatment.