ITP OD 150mg Tablet 10 'S

About

Dopamine and acetylcholine are two of the major neurotransmitters involved in several natural mechanisms. The gastric tract also releases dopamine from the stomach and influences GIT from its upper to the lower part.ITP OD 150mg Tablet 10 'S belongs to a class of drugs called “Prokinetic agents”, commonly referred to as gastro propulsive medicines used for the prevention and management of nauseous states. It also helps relieve symptoms of functional or non-ulcerative dyspepsia, a health condition that affects the stomach and normal bowel movements resulting in indigestion, nausea, and vomiting. As compared to some of the other propulsive drugs like Domperidone, it does not carry the same level of risk to the heart.

ITP OD 150mg Tablet 10 'S is chemically composed of Itopride which works by blocking the action of dopamine (D2 receptors) and enhances the effects of acetylcholine via inhibition of Acetylcholinesterase (AChE) in the gastric tract, providing a steady amount of acetylcholine responsible for smooth muscle contractions. The outcome of these actions is manifested in the form of enhanced gastric movements and digestion as well as increased pressure in the lower part of the esophagus (food pipe) that helps prevent the reflux of stomach contents. Through its action on the brain, it helps control vomiting too.  ITP OD 150mg Tablet 10 'S takes about 30 minutes to 1 hour to start working.

ITP OD 150mg Tablet 10 'S is available in the form of oral tablets and capsules on prescription to be swallowed via mouth with a glass of water, 1 tablet is usually 2 to 3 times a day or just once if slow release (SR) formulation is being taken, follow the advice by the doctor. Do not crush or chew the tablet.  It works better if you take it at least 30 minutes before your meal. ITP OD 150mg Tablet 10 'S can be safely prescribed to adults and children above 17 years of age. In case of pregnancy and lactation, ask your doctor first due to potentially harmful effects on the unborn baby. The most common side effects observed with ITP OD 150mg Tablet 10 'S are drowsiness, diarrhea, fatigue, dry mouth, etc. 

Indications

ITP OD 150mg Tablet 10 'S is prescribed to adults to treat:

• Functional Dyspepsia 
• Gastritis 
• Early satiety 
• Nausea 
• Vomiting 
• Heartburn 
• Dyspepsia 
• Epigastric pain (Abdominal pain)

How ITP OD 150mg Tablet 10 'S Works

ITP OD 150mg Tablet 10 'S is chemically composed of Itopride which works by blocking the action of dopamine (D2 receptors) and enhances the effects of acetylcholine via inhibition of Acetylcholinesterase (AChE) in the gastric tract,  providing an increased amount of acetylcholine responsible for smooth muscle contractions. The outcome of these actions is manifested in the form of enhanced gastric movements and digestion as well as increased pressure in the lower part of the esophagus (food pipe) that helps prevent the reflux of stomach contents. 

How to use ITP OD 150mg Tablet 10 'S

ITP OD 150mg Tablet 10 'S is available in the form of oral tablets and capsules. Swallow the medicine with a glass of water without chewing for 30 minutes before taking a meal. ITP OD 150mg Tablet 10 'S is preferably taken at the same time every day till the prescribed time to maintain equal blood levels at all times. ITP OD 150mg Tablet 10 'S is taken orally in tablet or capsule form as per recommended doses. It also depends on the release mechanism of the medicine. Regular tablets are taken 2 to 3 times a day, whereas sustained release formulations may be taken just once, follow your doctor’s advice.  

It is usually taken at 8 to 12 hourly intervals or once every 24 hours before a meal.  ITP OD 150mg Tablet 10 'S should be taken at a set time and for the prescribed length of time, not exceeding it. The patient in general starts to feel better in a couple of days, make sure to complete the entire course even if you feel better. Treatment can last for several weeks depending on your condition. 

Available Potency and forms of ITP OD 150mg Tablet 10 'S 

• 50 mg      -    Tablet/ Capsule
• 150 mg    -    Tablet/ Capsule

Regular Tablets: These tablets start releasing their chemical components and begin the absorption process right after consuming them and may be required to take at regular intervals throughout the day

Sustained Release (SR): These types of medicines are formulated to release their chemical contents slowly after ingestion over some time to allow patients to gain benefits on a prolonged basis. Usually, these maintain steady levels in the blood and are required to be taken once or twice. These are labeled as “SR” at the end of the brand name.

Dosage

Adult Dosage

ITP OD 150mg Tablet 10 'S is taken orally, 1 tablet of 50 mg thrice a day at 8 hourly intervals before meals

Or, 

150 mg once a day orally before meals

Pediatric Dose

Not recommended for children or adolescents under 18 years of age

Elderly Dose

The exact dose must be determined by your doctor, ideally being the lowest effective due to serious side effects which may be more pronounced in elderly patients. Especially those taking any other medication concurrently. Seek a doctor’s advice. 

Pregnancy use and Lactation

Regarding the safety of ITP OD 150mg Tablet 10 'S consult your doctor first if you are pregnant, trying to conceive a baby, or are breastfeeding an infant. ITP OD 150mg Tablet 10 'S has limited safety data available and must not be taken without consulting a doctor first. Your doctor will only prescribe if it is considered extremely necessary.

Contraindications

 ITP OD 150mg Tablet 10 'S should not be prescribed under the following circumstances:

• Allergy to the contents of  ITP OD 150mg Tablet 10 'S
• Gastric bleeding
• Gastric perforation 
• Mechanical obstruction of GI tract
• Increased  gastrointestinal motility
• Pregnancy 
• Parkinson's disease
• Patients under 18 years of age

Precautions‌ ‌

Please‌ ‌tell‌ ‌your‌ ‌doctor‌ ‌about‌ ‌any‌ ‌of‌ ‌the‌ ‌following‌ ‌conditions‌ before starting or during the treatment with ‌ITP OD 150mg Tablet 10 'S:‌ 

• Caution is advised if you have a history of drug allergies 
• Patients suffering from chronic gut disease must be careful, especially those with a history or an existing Gastrointestinal Perforation/ bleeding must avoid it
• ‌ITP OD 150mg Tablet 10 'S works better if taken 30 minutes before a meal. Taking it after the meal will slow down its function
• Alcohol consumption may potentiate the side effects, it must be avoided or restricted with ‌ITP OD 150mg Tablet 10 'S
• While using ‌ITP OD 150mg Tablet 10 'S in the elderly population (65 years and above) careful consideration and monitoring are advised due to the increased impact of side effects
• ITP OD 150mg Tablet 10 'S is known to cause dizziness or blurred vision, it is important that you know how your body responds to the drug. Avoid driving or using heavy/sharp machinery if you experience any such symptom
• Compromised liver function can negatively affect your body since ‌ITP OD 150mg Tablet 10 'S is largely processed in it, discuss it with your doctor. 
• ITP OD 150mg Tablet 10 'S when used for longer periods, especially in elderly patients can result in this condition. Make sure to follow the doctor’s prescription and monitor the patient during treatment
• If you are a pregnant or lactating mother, consult a doctor first to determine if ‌ITP OD 150mg Tablet 10 'S is safe for you.

Interaction With Other Medications

Following drugs can have some interactions with ITP OD 150mg Tablet 10 'S and can potentiate or reduce the effects when used concomitantly. Some of these drugs are:

• Cimetidine
• Ranitidine
• Teprenone 
• Cetraxate

Adverse effects

Like most medicines, ITP OD 150mg Tablet 10 'S has some side effects which include:

Common Side effects:

• Constipation /Diarrhea  
• Headache 
• Dry mouth 
• Skin rash
• Pruritis 
• Abdominal cramps 

Less Common side effects:

• Anaphylactic reaction 
• Blurred vision
• Fatigue 
• Restlessness/ agitation 
• Loss of appetite 
• Nervousness 
• Anxiety 
• Thrombocytopenia 
• Leukopenia 
• Inability to urinate (urinary retention)
• Breast tenderness 
• Gynecomastia 
• Increased prolactin levels 
• Arrhythmias 
• Disturbance in the liver enzymes /  LFTs
• Jaundice 

 HOW TO COPE-UP  WITH ADVERSE EFFECTS

Allergic Reactions - Allergic reactions to the drug may be mild to severe or potentially could be life-threatening. If allergy is suspected immediately take anti-allergy (antihistamine) medicine which will stop the mild reaction. If a serious allergic reaction is suspected, rush to the nearby hospital and avoid ITP OD 150mg Tablet 10 'S and drugs with similar compounds in the future.

Dry Mouth - Can be helped by sipping water throughout the day, chewing sugarless gum, using alcohol-free mouthwash, allowing ice to melt in the mouth, or using a saliva substitute.

Headaches - In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe

Skin Rash - Can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. Antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.to bring ease as well. Avoid high-intensity exercise while suffering from muscular pain.

Constipation - Can be combated by adding more fibers to the patient’s diet, asking the patient to drink plenty of fluids, and increasing their physical activity to trigger contractions in the intestines.

Fatigue - Patients experiencing this adverse effect are advised to take deep breaths, intake tea or coffee, get a good night’s rest, and not overburden themselves for a few days.

FAQ's

#1. How Does ITP OD 150mg Tablet 10 'S Work?

ITP OD 150mg Tablet 10 'S shows enhanced digestive effects on the body by inhibiting certain chemicals such dopamine and acetylcholinesterase, which mediate prokinetic effects. It affects the tone of the food pipe (esophagus) and contractive forces of peristalsis aid in digestion, and help prevent reflux of stomach contents as well as prevent vomiting. 

#2. For How Long Should I Take ITP OD 150mg Tablet 10 'S? 

ITP OD 150mg Tablet 10 'S is taken as per doctors' recommendation, depending on your condition. The commonly prescribed duration may vary, follow your prescription strictly. 

#3. Is ITP OD 150mg Tablet 10 'S Highly Addictive?

No, it is not considered to be addictive and does not cause any dependence (physical and psychological)

#4. Can I Drink Alcohol With ITP OD 150mg Tablet 10 'S?

Consuming alcohol when taking ITP OD 150mg Tablet 10 'S may cause excessive drowsiness and could increase the risk of side effects, hence should be avoided or restricted to small amounts. 

#5. What If I Take Too Much Of ITP OD 150mg Tablet 10 'S?

If you have taken too much of the prescribed ITP OD 150mg Tablet 10 'S you may experience symptoms of overdose, for example, fast or irregular heartbeat, upset stomach, blurred vision, fainting, dizziness, abdominal pain, or life-threatening severe symptoms. Contact your doctor or rush to the nearby emergency immediately if you have any of these symptoms. 

#6. What If I Forget To Take ITP OD 150mg Tablet 10 'S?

ITP OD 150mg Tablet 10 'S is taken 2-3 times a day or just once, before meals so you can take the missed dose as soon as you remember unless it's less than 6 hours until your next dose if you are taking regular tablets. If the period for the next period is near, you should skip the missed dose. If it helps to remind you, set an alarm or use a pill organizer or a mobile application so you do not miss any dose. Make sure to complete your course of treatment even if you feel better and think you do not need to take it anymore.

#7. Can I Take ITP OD 150mg Tablet 10 'S During Pregnancy Or Breastfeeding?

ITP OD 150mg Tablet 10 'S has a safety concern for pregnant women and breastfed infants. If you are pregnant, think you may be pregnant, or are planning to conceive a baby, please consult your doctor before using ITP OD 150mg Tablet 10 'S. Also if you are breastfeeding, please consult your doctor before taking ITP OD 150mg Tablet 10 'S. 

#8. Can I Drive Or Ride A Bike After Taking ITP OD 150mg Tablet 10 'S?

ITP OD 150mg Tablet 10 'S can cause drowsiness and dizziness so make sure you know how your body reacts while using ITP OD 150mg Tablet 10 'S. Do not drive or use any machinery/sharp tools until you feel normal again

#9. How Should ITP OD 150mg Tablet 10 'S Be Stored?

Store it at room temperature, away from excess heat, direct sunlight, and moisture. Make sure it is not consumed by pets, children, and other people. Dispose of unused medicine when treatment is over.

#10. Are there any lifestyle changes that can help me with my condition?

Small changes in your daily lifestyle can help you with symptoms of GERD, indigestion, and heartburn. 

• Quit or limit smoking to the minimum 
• Avoid lying down immediately after taking meals
• Try to incorporate healthy food options into your meals such as fresh fruits and vegetables, more fiber and protein
• Regularly do some sort of physical exercise like walk
• Controlling weight also helps with such symptoms
• Avoid or restrict caffeinated drinks or citrus products that can trigger acid reflux 
• Properly chew your food slowly before swallowing