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gravinate-12.5mg/4ml-syrup-60-ml
12% off

Gravinate 12.5mg/4ml Syrup 60 ml


FORMULADimenhydrinate 12.5 mg / 4 ml
COMPANYSearle Pharma
TYPESyrup
About

About

Gravinate 12.5mg/4ml Syrup 60 ml is an anti-emetic medicine and belongs to a class of drugs called Antihistamines. Based on the mechanism of action, it belongs to the H1- antagonist pharmacological group used to manage conditions like motion sickness resulting in nausea, vomiting, and vertigo. Gravinate 12.5mg/4ml Syrup 60 ml also has sedative potential manifested in the form of drowsiness, so precautions should be taken accordingly. Dimenhydrinate is available as oral tablets, IV solution as well as oral syrup to be taken strictly under a doctor’s prescription. 

Gravinate 12.5mg/4ml Syrup 60 ml is chemically composed of Dimenhydrinate whose exact working mechanism is not well understood. However, it is thought that it works by blocking the effects of released histamine from H-1 receptors, a chemical agent involved in gastric muscle contraction and its secretion. It possesses antimuscarinic action and sedative properties as well. Adequacy of liver function must be ensured since this drug is processed by the liver mainly. It takes about 15 to 30 minutes for symptoms to improve after oral intake. 

Gravinate 12.5mg/4ml Syrup 60 ml is available in the form of oral syrup on prescription to be swallowed via mouth with a glass of water, usually in prescribed doses at 4 to 6 hours intervals in a day or as advised by the doctor. When using it for motion sickness, take it at least 30 minutes before the journey or activity triggering motion sickness starts. Gravinate 12.5mg/4ml Syrup 60 ml is more suited for children between the ages of 2 to 11 years due to easy intake and compliance. In case of pregnancy and lactation, ask your doctor first due to potentially harmful effects on the unborn baby.  The most common side effects observed with Gravinate 12.5mg/4ml Syrup 60 ml are drowsiness, constipation, loss of appetite, tinnitus, and others.

Indications

Gravinate 12.5mg/4ml Syrup 60 ml is prescribed to adults and children alike and it is used in the treatment of motion sickness causing:

  • Nausea 
  • Vomiting 
  • Vertigo 

How does Gravinate 12.5mg/4ml Syrup 60 ml work?

H-1 receptors are present on a variety of biological membranes inducing different responses when stimulated. The gastric tract also contains these receptors the effect of which is seen in form of smooth muscle contractility when induced.  It helps with motion sickness by blocking the effects of released histamine, slowing down the motility, and helps with vertigo through its antimuscarinic activity. Moreover, it readily spreads across the brain, causing a sedative effect.

How to use Gravinate 12.5mg/4ml Syrup 60 ml?

Gravinate 12.5mg/4ml Syrup 60 ml is available in the form of oral syrup to be taken by mouth. Swallow the syrup with a glass of water, at least 30 minutes before setting off for a journey or anything likely to cause motion sickness. In general, the treatment with Gravinate 12.5mg/4ml Syrup 60 ml is prescribed as per need, taken every 6 to 8 hours or as needed. Dosage is dependent upon your age, weight, condition, and response to the treatment, taking more than advised is likely to cause side effects.

Make sure to follow the doctor’s advice carefully regarding dosage and proper use. The syrup is packaged in a glass bottle. Do not household spoons to measure the syrup dose. A calibrated spoon/cup is available with ‌Gravinate 12.5mg/4ml Syrup 60 ml for dosing purposes. Alternatively, a syringe can be bought from a pharmacy., which can be used after removing the needle.

Available Potency of Gravinate 12.5mg/4ml Syrup 60 ml 

  • 12.5 mg/ 4 ml - Syrup

Dosage

Adult Dose

Tablet form is given to adults and adolescents in the prescribed dosage.

Child Dose

Gravinate 12.5mg/4ml Syrup 60 ml is not prescribed to children under 2 years of age due to unestablished safety. Following dosage is recommended, follow your doctor’s advice:

2 to 6 years: 12.5 - 25 mg 6 - 8 in a day

Maximum safe Dose: 75 mg in a day

6 to 11 years: 25 - 50 mg orally every 6 to 8 hours in a day

The maximum safe dose per day is 150 mg 

12 years and above: Same Adult dose

Elderly Dose

The syrup form is more suited for children and tablets, or injections are given to elderly people. Gravinate 12.5mg/4ml Syrup 60 ml must be used with caution in patients aged 60 and above. Dose adjustment may be required in case of impaired renal or heart function. Your physician will set the dose most appropriate for your health status. 

*Special Dose 

Liver Disease: Caution should be practiced, dose adjustment may be required 

Pregnancy use and lactation

Gravinate 12.5mg/4ml Syrup 60 ml is classified as a pregnancy category B drug by FDA (meaning no evidence of any risk in controlled animal trials but regarding the human fetus, insufficient data is available). It is advised if you are pregnant or are planning to conceive, please consult your doctor before using Gravinate 12.5mg/4ml Syrup 60 ml. Gravinate 12.5mg/4ml Syrup 60 ml is also secreted in human milk in little amount, if you are breastfeeding, please consult your doctor before taking Gravinate 12.5mg/4ml Syrup 60 ml. 

Contraindications

Please inform your doctor if you have a history of any before using Gravinate 12.5mg/4ml Syrup 60 ml:

  • Allergic reaction to Gravinate 12.5mg/4ml Syrup 60 ml or similar drugs
  • Severe Liver disease 
  • Enlarged prostate 
  • Asthma or chronic lung disease 
  • Glaucoma 
  • Pregnancy 
  • Porphyria 

Precautions‌ ‌

Please‌ ‌tell‌ ‌your‌ ‌doctor‌ ‌about‌ ‌any‌ ‌of‌ ‌the‌ ‌following‌ ‌conditions‌ before starting or during the treatment with ‌Gravinate 12.5mg/4ml Syrup 60 ml:‌ ‌

  • Make sure to rule out any allergies to  ‌Gravinate 12.5mg/4ml Syrup 60 ml or any similar drug
  • Do not use household spoons to measure the syrup dose. A calibrated spoon/cup is available with ‌Gravinate 12.5mg/4ml Syrup 60 ml for dosing purposes. Alternatively, a syringe can be bought from a pharmacy.
  • Compromised liver function can negatively affect your body since ‌Gravinate 12.5mg/4ml Syrup 60 ml is largely processed in it, discuss it with your doctor. 
  • Elderly patients (65 years and above) should exercise caution, especially if they are feeble and lack balance or have gait problems
  • Watch out for the signs of increased excitation in children or hyperactivity following intake of ‌Gravinate 12.5mg/4ml Syrup 60 ml
  • Gravinate 12.5mg/4ml Syrup 60 ml has a direct effect on the brain causing drowsiness, avoid driving or any activity involving sharp or heavy tools
  • Be protective against falls or injury
  • Alcohol consumption must be avoided with Gravinate 12.5mg/4ml Syrup 60 ml
  • Gravinate 12.5mg/4ml Syrup 60 ml can an addicting effect on some individuals, misuse of Gravinate 12.5mg/4ml Syrup 60 ml must be avoided
  • Avoid using Gravinate 12.5mg/4ml Syrup 60 ml  if you suffer from lung disease or have breathing problems
  • Monitor the improvement in your symptoms, in case there is no difference ask your doctor
  • Gravinate 12.5mg/4ml Syrup 60 ml can cause tinnitus of the ears, if you are using any medicine for ear conditions, it may mask this side effect
  • Patients with seizures or a history of convulsions should be very careful while using Gravinate 12.5mg/4ml Syrup 60 ml 

Interaction with other medications

Certain medications could interact with Gravinate 12.5mg/4ml Syrup 60 ml and may increase or decrease its absorption, in which case, your doctor might alter your dosage. A few of these interacting drugs are given below:

  • Topical or oral Antihistamines 
  • Antidepressants like MAO Inhibitors
  • General anesthetics 
  • Anti-Parkinson Drugs  
  • Tricyclic Antidepressants 
  • Alcohol 
  • Hypnotics 
  • Anxiolytics 
  • Metoclopramide 
  • Muscle relaxants 
  • Ototoxic drugs 

Adverse effects

Like most medicines, Gravinate 12.5mg/4ml Syrup 60 ml has some side effects which include:

Common Side effects

  • Constipation or Diarrhea  
  • Headache 
  • Drowsiness 
  • Tinnitus 
  • Skin rash

Rare side effects

  • Anaphylactic reaction 
  • Blurred vision
  • Fatigue 
  • Blurred vision 
  • Restlessness/ agitation 
  • Loss of appetite 
  • Glaucoma 
  • Dilated pupils 
  • Inability to urinate (urinary retention)
  • Mental confusion/irritation 
  • Porphyria 
  • Palpitations 
  • Tachycardia 
  • Euphoria 
  • Delirium 

LIST OF HOW TO DEAL WITH ADVERSE EFFECTS

  • Feeling or being sick (nausea or vomiting) or diarrhea -Avoid eating rich or spicy food. It might help to take medication after food. If you're sick, try drinking small, frequent sips of water.
  • Fatigue - Patients experiencing this adverse effect are advised to take deep breaths, intake tea or coffee, get a good night’s rest, and not overburden themselves for a few days.
  • Feeling drowsy - If the medication makes you feel drowsy or sleepy, stop what you're doing and sit or lie down until you feel better, and do not rise too fast or immediately from a sitting or lying down position to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Headaches - In which case make sure you rest and drink plenty of fluids. Avoid the use of alcohol. Take a prescribed painkiller. Consult your doctor if the headaches last longer than a week or are severe
  • Feeling dizzy (lightheaded) or weak - If the medication makes you feel dizzy or weak, stop what you're doing and sit or lie down until you feel better, and do not rise too fast or immediately from sitting or lying down to a standing posture. Do not drive or use tools or machinery in case of any of these effects.
  • Photosensitivity - Patients are asked to wear sun-protective clothes when going outside including gloves and a hat, to apply generous amounts of broad-spectrum sunblock along with wearing sunglasses. Patients are advised to do all necessary work after sunset to reduce or eliminate sun exposure while undergoing treatment with Gravinate 12.5mg/4ml Syrup 60 ml.
  • Skin Rash - Can be eased by applying soothing and healing lotions or creams such as calamine lotion/cream. Apply a cold compress to the rash to help reduce itchiness and redness caused by the rash. Antihistamine (prescribed by a doctor) is also recommended as an effective way to combat any skin rash.
  • Blurred vision - This side effect tends to go away on its own in a few days; patients are advised to not operate heavy machinery or drive any motorized vehicles in the meantime. If blurred vision persists, please contact your doctor.

FAQs

#1. WHAT EXACTLY DOES Gravinate 12.5mg/4ml Syrup 60 ml DO?

Gravinate 12.5mg/4ml Syrup 60 ml helps relieve symptoms of motion sickness causing dizziness, nausea, and vomiting.

#2. HOW LONG WILL I HAVE TO TAKE Gravinate 12.5mg/4ml Syrup 60 ml FOR?

 Gravinate 12.5mg/4ml Syrup 60 ml is usually taken as per need and not a long-term course

#3. HOW LONG DOES IT TAKE FOR Gravinate 12.5mg/4ml Syrup 60 ml TO START WORKING?

The onset of action normally starts working within 30 minutes to 1 hour of ingestion

#4. CAN I STOP TAKING Gravinate 12.5mg/4ml Syrup 60 ml?

Gravinate 12.5mg/4ml Syrup 60 ml is taken as per need and it must not be taken more than required

#5. WHAT IF I TAKE TOO MUCH OF Gravinate 12.5mg/4ml Syrup 60 ml?

If you have taken too much of the prescribed Gravinate 12.5mg/4ml Syrup 60 ml you may experience symptoms of overdose, for example, fast pounding, irregular heartbeat, upset stomach, blurred vision, fainting, dizziness, seizures, or life-threatening severe symptoms. Contact your doctor immediately and rush to a nearby hospital if you have any of these symptoms. toxicity can be fatal if left unattended.

#6. CAN I TAKE Gravinate 12.5mg/4ml Syrup 60 ml DURING PREGNANCY OR BREASTFEEDING?

Gravinate 12.5mg/4ml Syrup 60 ml may have a safety concern for the unborn baby, hence not advised without a doctor’s consultation. If you are pregnant, think you may be pregnant, or are planning to have a baby, please consult your doctor before using Gravinate 12.5mg/4ml Syrup 60 ml. If you are breastfeeding, please consult your doctor before taking Gravinate 12.5mg/4ml Syrup 60 ml. 

#7. CAN THE USE OF Gravinate 12.5mg/4ml Syrup 60 ml CAUSE DROWSINESS?

It causes drowsiness, dizziness, and visual disturbances. If you experience any of these symptoms avoid driving or operating heavy machinery or sharp tools.

#8. HOW SHOULD Gravinate 12.5mg/4ml Syrup 60 ml BE STORED?

Store it at room temperature, away from excess heat, direct sunlight, and moisture. Make sure it is not consumed by pets, children, and other people. Dispose of the unused medicine. Store it between 15 to 25 °C 

#9. CAN I DRIVE OR RIDE A BIKE AFTER TAKING Gravinate 12.5mg/4ml Syrup 60 ml?

Usually Gravinate 12.5mg/4ml Syrup 60 ml  is known to cause dizziness so to make sure you know how your body reacts while using ‘product’. Do not drive or use any machinery until you feel normal again.

#10. CAN I DRINK ALCOHOL WITH Gravinate 12.5mg/4ml Syrup 60 ml?

Gravinate 12.5mg/4ml Syrup 60 ml is known to cause drowsiness, hence taking alcohol with this drug is strictly not advised.

Add to Cart

1 Pack = 60ml Syrup(s)
Rs. 42.92Rs. 48.77
12% off