Clenil Inhaler 250mcg 1 'S

About

Clenil Inhaler 250mcg 1 'S is an inhaled steroid, available in a readily absorbable form, intended to prevent asthma. Clenil Inhaler 250mcg 1 'S contains “Beclomethasone Dipropionate” as an active therapeutic agent - a prodrug containing anti-inflammatory and anti-allergic properties. Clenil Inhaler 250mcg 1 'S is supposed to be administered in individuals older than 4 years of age, for the maintenance and prophylaxis of asthma. 

Clenil Inhaler 250mcg 1 'S is also used off-label for the management of chronic obstructive pulmonary disease. Its major use is for the prevention of airways obstruction which is why it is known as a “Preventer inhaler”. Clenil Inhaler 250mcg 1 'S clears the airways by acting on the glucocorticoid receptor. Usage of Clenil Inhaler 250mcg 1 'S is not associated with the side effects that are typically caused by corticosteroids, as it remains only locally active in the lungs. 

It’s a point of consideration that Clenil Inhaler 250mcg 1 'S is not a rescue medication for an acute asthmatic attack. If a person has an asthmatic attack, he should be rescued with a fast-acting inhaler which Clenil Inhaler 250mcg 1 'S is not. Medical help is advised if breathing difficulty worsens now. 

Indications

• Control of the development of asthma

• Chronic Asthma 

• Chronic Obstructive Pulmonary Bronchitis (Off-label)

• Allergic Rhinitis 

How Does Clenil Inhaler 250mcg 1 'S Work

Clenil Inhaler 250mcg 1 'S contains “Beclomethasone dipropionate” as an active therapeutic agent - a glucocorticoid, that reduces inflammation by inhibiting inflammatory mediators. The active agent has weak receptor binding affinity and is therefore readily converted into its active form, 17 monopropionate (17-BMP), right after administration. 17-BMP efficiently binds to the glucocorticoid receptor resulting in anti-inflammatory action by inhibiting pro-inflammatory factors e.g., Cytokines, chemokines, and adhesion molecules. 

How To Use Clenil Inhaler 250mcg 1 'S

For the first time usage or usage after three days, softly remove the mouthpiece and release the actuation to check if it’s working properly. The actuator should be taken between the index finger and thumb. Then place the mouthpiece between the lips and make a complete expiration. Press the actuation with your index finger and take a deep inspiration only once. Hold your breath if possible and release steadily. Close the mouthpiece with a cap after the actuation. 

Dosage

Clenil Inhaler 250mcg 1 'S is available as a pressurized inhalation solution of 50mg. Each actuation delivers a dose of 250mcg, providing 200 inhalations in total. 

Adult Dose

From 2 inhalations twice a day to 1 inhalation 4 times a day, the therapy can be increased up to 2 inhalations 3 to 4 times a day at times of need. 

The dose is reduced when asthma is stabilized, and the total daily dose is taken as two to four divided doses. 

Pediatric Dose

A lower strength (50 or 100 mcg) inhaler may be more suitable for children with regards to safety. Discuss dosage with your doctor

Pregnancy And Lactation

Safety of Clenil Inhaler 250mcg 1 'S is not established in pregnant and lactating women. It should be administered during pregnancy and lactation only if the expected benefit to the mother is more than the risk to the fetus. 

There is a possibility of hypoadrenalism in the newborns whose mothers were on Clenil Inhaler 250mcg 1 'S during pregnancy so they should be closely monitored for this side effect. 

Contraindications

The use of Clenil Inhaler 250mcg 1 'S is contraindicated in the following cases:

• Hypersensitivity to the drug or any excipients. 

• Acute bronchospasm 

• Local viral infections

• Tuberculosis

Precautions

• Clenil Inhaler 250mcg 1 'S should not be abruptly stopped and the doses should be administered if the physician suggests. 

• Tell your doctor if you had osteoporosis, cataract, glaucoma, or tuberculosis in the past or you recently had a fungal, viral, or bacterial infection. 

• People who are receiving long-term treatment of steroids or those who are taking high doses should be treated with special care. The individual should be stable before initiating the treatment with Clenil Inhaler 250mcg 1 'S and systemic steroid should be gradually withdrawn. In addition, the adrenocortical function should be regularly monitored. 

• Some patients may feel throat irritation upon administration of Clenil Inhaler 250mcg 1 'S. They should thoroughly rinse their mouth after inhalation. 

• Clenil Inhaler 250mcg 1 'S should not be used in acute asthmatic attacks. It is intended to be used for the long-term management of asthma. 

• People who are switched from systemic steroid therapy to inhaled steroid therapy may develop allergies such as eczema and rhinitis. The allergies are unmasked that were previously suppressed by systemic steroids. Treatment with antihistamines and topicals can be considered in that case. 

• Due to the presence of ethanol, Clenil Inhaler 250mcg 1 'S should be used with caution in patients having alcoholism, active liver disease, epilepsy, and cerebral pathologies. 

Interactions With Other Medications

Clenil Inhaler 250mcg 1 'S shows interactions with the following medications:

• Aldesleukin

• BCG vaccine 

• Hyaluronidase

• Leflunomide

• Macimorelin

• Natalizumab

• Pimecrolimus

• Tacrolimus 

Adverse Effects

Common Side Effects 

• Candidiasis of the mouth and throat 

• Pharyngitis 

• Headache

• Upper respiratory tract infection 

• Dry mouth 

• Hoarseness (Throat irritation) 

Less Common Adverse Effects 

• Wheezing

• Hypersensitivity reactions such as urticaria, rashes, pruritis, and angioedema. 

• Psychiatric disorders such as disturbed sleep patterns, behavioral changes, anxiety, and depression. 

How To Cope with Some of The Adverse Effects

• Upper Respiratory Tract Infections - Use nasal decongestant if you have difficulty in breathing, steam inhalation, or gargling with salt water to aid in clearing the airways. Take antibiotics upon your doctor’s suggestion for subsiding the infection. 

• Dry Mouth - Drink plenty of water to keep yourself hydrated, refrain from dehydrating habits such as holding thirst, chew sugarless gums, and rinse your mouth with an alcohol-free mouthwash. 
• Wheezing - Use a humidifier to keep humidity retained in your room, take warm drinks, cease smoking, and practice breathing in the clean air. 
• Headache - Using a cold pack or hot compress helps in relieving headaches, caffeine helps reduce pain, you can also take an over-the-counter analgesic medication if pain persists. 

Key Facts About Clenil Inhaler 250mcg 1 'S

• Clenil Inhaler 250mcg 1 'S is a metered-dose corticosteroid that is intended for the prevention of asthma. 

• It is not a rescue medication for immediate relief from asthmatic attacks as it’s not a fast-acting inhaler.

• Clenil Inhaler 250mcg 1 'S is also prescribed off-label for the management of chronic obstructive pulmonary bronchitis (COPD). 

• Some patients may experience hoarseness or throat irritation upon administration of Clenil Inhaler 250mcg 1 'S, they should immediately rinse their mouth after actuation. 

FAQs

#1. What Is Clenil Inhaler 250mcg 1 'S Used For?

Clenil Inhaler 250mcg 1 'S is a slow-acting drug and therefore is recommended to be usually twice to relieve breathlessness and similar symptoms. 

#2. How To Store Clenil Inhaler 250mcg 1 'S?

Clenil Inhaler 250mcg 1 'S is to be kept away from the reach of children, in a cool dry place away from direct sunlight and humidity as that tends to ruin certain drugs. Clenil Inhaler 250mcg 1 'S must be maintained in settings below 25*C, do not refrigerate or freeze Clenil Inhaler 250mcg 1 'S.

#3. Will Clenil Inhaler 250mcg 1 'S affect my sexual activity?

No, there isn't sufficient evidence to suggest that patients experience a decrease in libido.

#4. Is it safe to have painkillers while taking Clenil Inhaler 250mcg 1 'S?

Yes, Over the counter painkillers such as paracetamol are safe to be ingested along with Clenil Inhaler 250mcg 1 'S under the supervision of a doctor. NSAIDs like ibuprofen, aspirin, and others are known to interact with Clenil Inhaler 250mcg 1 'S, discuss with your doctor

#5. Is it safe to have Clenil Inhaler 250mcg 1 'S along with oral contraceptives?

Yes, there is no evidence to suggest that Clenil Inhaler 250mcg 1 'S interacts with oral contraceptives.

#6. How Can I Clean My Inhaler?

Make sure to properly clean your inhaler at least once every week. Canisters can be taken out from the plastic body, rinse the plastic body and mouthpiece cap with an adequate amount of lukewarm tap water. Leave them out to dry before putting them back in the canister. The mouthpiece covering should be replaced frequently

#7. HOW LONG DOES IT TAKE FOR Clenil Inhaler 250mcg 1 'S TO BE EFFECTIVE?

The betterment in the pulmonary function is visible in 1 to 4 weeks after starting the treatment with Clenil Inhaler 250mcg 1 'S. 

#8. CAN I TAKE Clenil Inhaler 250mcg 1 'S IN AN ACUTE ASTHMATIC ATTACK?

Clenil Inhaler 250mcg 1 'S should not be taken as a rescue medicine to immediately relieve the symptoms of acute asthma. A fasting-acting inhaler is usually recommended instead. 

#9. IS LONG-TERM USE OF Clenil Inhaler 250mcg 1 'S SAFE?

Clenil Inhaler 250mcg 1 'S is unlikely to cause adverse effects if you use it according to the doctor’s advice. The metered dose limits the steroid to produce greater side effects as only a small amount of medicine is being delivered across the lungs. However, more than recommended doses can put a person at risk of developing adrenal gland problems, and osteoporosis. 

#10. CAN A PREGNANT OR NURSING MOTHER TAKE Clenil Inhaler 250mcg 1 'S?

Safety in pregnant or breastfeeding women is not evident. However, Clenil Inhaler 250mcg 1 'S should only be given if the benefit to the mother is greater than the risk to the infant.

#11. WHAT ARE THE STORAGE CONDITIONS OF Clenil Inhaler 250mcg 1 'S?

Clenil Inhaler 250mcg 1 'S should be stored at room temperature, away from moisture and direct heat. The canister should not be pierced or burnt, neither it should be frozen. 

#12. WHAT WILL HAPPEN IF I ABRUPTLY STOP USING Clenil Inhaler 250mcg 1 'S?

Clenil Inhaler 250mcg 1 'S should not be stopped abruptly as the breathing difficulty may relapse. Sudden withdrawal may make you feel wheezy, there will be shortness of breath, tightness of the chest, and cough. So, the treatment duration must be followed as per the doctor’s advice.

#13. DO LIFESTYLE CHANGES HELP IN RELIEVING ASTHMA?

Lifestyle changes help treat asthma at a faster rate and reduce breathing difficulties. Healthy practices to achieve this are Smoking cessation, regular exercise, and healthy food intake. 

#14. Can I DRIVE A BIKE AFTER USING Clenil Inhaler 250mcg 1 'S?

Clenil Inhaler 250mcg 1 'S does contain a small amount of ethanol, but it usually does not make it difficult to ride a vehicle. However, if you feel drowsy due to the underlying disease, you should consider avoiding vehicles and lifting heavyweights.