Bofalgan IV 1gm/100ml Injection 100 vial

Bofalgan IV 1gm/100ml Injection 100 vial belongs to a group of medicines called analgesics or painkillers. It is used for short-term management of mild to moderate pain and fever, commonly in the post-operative rehabilitation phase. The medicine is effective against headaches, toothaches, backaches, menstrual cramps, and even joint pain. Alternatively, paracetamol is also known as acetaminophen.

Bofalgan IV 1gm/100ml Injection 100 vial can be used in combination with other medicines or alone as directed by the physician. Bofalgan IV 1gm/100ml Injection 100 vial is available in many different formulations such as tablets, syrup and suspension, and injectable form. These multiple formulations aid in providing precise dosages to patients of varying ages and severity of conditions.

Caution is advised prior to usage in alcoholics with impaired liver function, and malnourished individuals.

How Does Bofalgan IV 1gm/100ml Injection 100 vial Work

The exact mode of action is unknown. It is thought to work by acting on the hypothalamus, thereby reducing fever. This medication is also known to block the release of certain chemicals called prostaglandins involved in pain and inflammatory reactions,  which in turn block pain impulse generation.

Bofalgan IV 1gm/100ml Injection 100 vial is used to treat:

• Mild to moderate pain such as migraine, and menstrual pain.
• Fever (also fever associated with COVID-19)
• Musculoskeletal pain 

Dosage

Adult Dosage

Bofalgan IV 1gm/100ml Injection 100 vial can be given via intravenous infusion according to the patient's body weight and requirement. The maximum safe dose must not exceed 4 grams per day in healthy adults with adequate renal and liver function. 

Patients weighing 50 kgs or more: 1g per 100 ml via slow infusion over a period of 15-20 minutes, 6 hourly.

Patients weighing 30-50 kg: 15mg/kg per 75 ml over a period of 15-20 minutes, 6 hourly, or 300mg/2ml IM 6 hourly.

Pediatric Dosage

For patients aged 12 and below, the syrup form of Bofalgan IV 1gm/100ml Injection 100 vial is commonly prescribed. However, the IV route can also be availed when indicated. 

10-50 kg: can be given 15mg/kg per 75 ml, 6 hourly. The maximum dose is 30mg/kg/day.

Below 10kg: 10 mg/kg (1 ml/kg), 6 hourly, Maximum dose is 30mg/kg/day.

Above 50kg: 1gm every 4 - 6 hours. The max dose is 4gm daily.

Maximum safe dose for 10-30 kgs: 2 g per day, in a child less than 2 years Bofalgan IV 1gm/100ml Injection 100 vial should not be used, unless advised by the doctor

Elderly Dosage 

Patients aged 65 years and older mostly start off at a lower dosage due to reduced kidney and liver function. In case of liver and kidney impairment, dose adjustment is required. 

Pregnancy Use And Lactation

Bofalgan IV 1gm/100ml Injection 100 vial is secreted into human milk and is usually safely taken by pregnant females. There is no evidence of risk in humans but if you are pregnant, think you may be pregnant, or are planning to have a baby, please consult your doctor before using Bofalgan IV 1gm/100ml Injection 100 vial. If you are breastfeeding, please consult your doctor before taking Bofalgan IV 1gm/100ml Injection 100 vial.

How To Use Bofalgan IV 1gm/100ml Injection 100 vial

The dosage is entirely dependent on the individual’s weight, age, fever, or pain symptoms. Bofalgan IV 1gm/100ml Injection 100 vial is an injectable solution that is given intravenously by a healthcare provider in a hospital or an IV line can be set up at home by a visiting health professional/nurse. In adults, via intravenous route, repeat a single dose of 1000 mg (1g) every 6 hours. The minimum interval should be 4 hours. When necessary it may be taken up to a maximum of 4 doses (4000 mg) in 24 hours. For infusion purposes, Bofalgan IV 1gm/100ml Injection 100 vial is diluted with compatible IV solutions such as sodium chloride, and ringers lactate, the ratio must be accurate. 

Like most medicines,Bofalgan IV 1gm/100ml Injection 100 vial has certain side effects:

• Pain at the site of injection or cannula 
• Phlebitis 
• Nausea
• Vomiting 
• Slight weakness/nervous feeling

Precautions

Please tell your doctor about any of the following conditions before using Bofalgan IV 1gm/100ml Injection 100 vial:

• Avoid injecting into arteries
• Impaired hepatic (liver) or renal (kidney) function (dose and timings of administration must be adjusted)
• Alcoholism
• Chronic malnutrition
• Dehydration
• G6PD deficiency (a genetic disorder)
• Hemolytic anemia (blood disorder due to premature destruction of red blood cells)
• Risk of serious skin reactions (in which case discontinue)

Contraindications

Please tell your doctor if you have a history of any of the following before using Bofalgan IV 1gm/100ml Injection 100 vial:

• Allergy to Bofalgan IV 1gm/100ml Injection 100 vial or any other medicine or food substance 
• Renal (kidney) impairment
• Hepatic (liver) impairment
• Malnutrition 
• Excessive alcohol consumption

#1. How long does it take for Bofalgan IV 1gm/100ml Injection 100 vial to start working?

Bofalgan IV 1gm/100ml Injection 100 vial usually takes less than 20-30 minutes to show analgesic effects.

#2. Can Bofalgan IV 1gm/100ml Injection 100 vial be taken with NSAIDs?

Though both are safe medicines, kindly consult your doctor before taking a combination of these two medicines together.

#3. How should I store Bofalgan IV 1gm/100ml Injection 100 vial?

Bofalgan IV 1gm/100ml Injection 100 vial should be stored at room temperature or in a cool, dry place (15-25 °C) away from light and moisture. Kindly put it out of reach of children and pets. Do not freeze the product.

#4. Will Bofalgan IV 1gm/100ml Injection 100 vial affect my fertility?

There is no known evidence of Bofalgan IV 1gm/100ml Injection 100 vial affecting fertility in either men or women.

#5. Does this medicine tend to affect contraception?

Bofalgan IV 1gm/100ml Injection 100 vial doesn't pose any effects on emergency contraception.

Please tell your doctor about the use of any of the following before using Bofalgan IV 1gm/100ml Injection 100 vial:

• Drugs that delay gastric (stomach) emptying (e.g anticholinergics, narcotics)
• Carbamazepine
• Amyl nitrite
• epinephrine/lidocaine (risk of methemoglobinemia)
• Metoclopramide
• Leflunomide 
• Oral anticoagulants
• Lomitapide 
• Hepatotoxic drugs
• Zidovudine
• Alcohol